Draw the reaction progress of thrombin

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Draw the reaction progress of thrombin

Question: A man with hemophilia (recessive sex-linked) has a daughter of normal phenotype. She marries a man who is normal for this trait. What is the probability that a daughter of this mating will be hemophiliac? That a son will be hemopholiac? If the couple has four sons, what is the probability that all foru will be hemophiliacs?

Question: Use the cleland representation draw the reaction progress of thrombin, a serene protease using a ping pong mechanism on the hydrolysis of the substrate Ala-Arg-Gly-Ala

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